Are the results likely biased toward the null?

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Are the results likely biased towards the null?

I read Field and colleagues' study (1) on the association of sports drinks and obesity risk among youth and young adults with great interest. Though there remains some uncertainty regarding the causative relationship between sugar-sweetened beverages (SSBs) and obesity risk, “the absence of evidence is not [always] the evidence of absence” (2). Therefore, it is perhaps wise that Field and colle...

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Are unadjusted analyses of clinical trials inappropriately biased toward the null?

See related article, pages 888–894. One of the delights of clinical practice has proven to be a major nuisance for clinical research: patients are nonidentical. Indeed, patients have multiple characteristics that influence the likelihood of the outcome of a disease, which can make it difficult in the extreme to accurately discern the effects of therapy from casual clinical experience or even ca...

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ژورنال

عنوان ژورنال: Obesity

سال: 2014

ISSN: 1930-7381

DOI: 10.1002/oby.20857